The only program I've used that detects these streams is MediaBox. When you get a URL similar to this:
http://stream.site.com/SHOW_ism/SHOW.ism/QualityLevels...
change it to this:
http://stream.site.com/SHOW_ism/SHOW.ism/Manifest
That said, most of the time these streams are DRM protected so even if you find the manifest for the stream and are able to capture it, the resulting file will be unusable because of the encryption. Also, the stream is usually built from many small chunks which then have to be assembled in order as well as combined, since the audio and video are separate, to make a single file. Non-DRM content shouldn't be a problem though. Use the manifest URL with ismdownloader for those streams.