I haven't used Mydeo, but there are several reasons to use it:

1. Mydeo has integrated its service into the popular home video editing package Windows Movie Maker 2 to allow users to upload their videos directly from its familiar interface. So you may use it on any PC with Windows XP SP2.
(I don't really like Windows Movie Maker, but I do think that it is a big advantage to be able to use the service on a huge amount of PCs)

2. Mydeo uses the Akamai Network for global storage and delivery together with secure streaming to guarantee security for Mydeo users’ content. This means that the humble home video maker can enjoy the quality and reliability of a world-leading streaming network, something they would never have been able to purchase as an individual.