It seems like the best solution is not to use an antivirus at all. Sounds stupid? Yes, if you use Windows.

But unlike Windows, Linux is a much safer operating system. In most cases you don't really need to install any antiviruses or firewall in Linux. While many of my friends suffer from viruses, I forgot about them since installing Ubuntu 9.10. Most software is still written for Windows, by I hardly use Windows XP on my virtual machine, because I found alternatives for most programs I used in Windows.

Sounds attractive? Don't be in a hurry to remove Windows completely. Just install Linux as a second operating system on your computer and see whether it is suitable for you.