I caught a virus on my desktop recently. I scanned my computer with Dr.Web, but it didn't find anything. Then I found a suspicious file and uploaded it to virustotal:
Kaspersky detected it as Trojan-Downloader.Win32.Small.jze, Microsoft as Trojan:Win32/Oficla.B.dll. Other antiviruses found nothing!.

I submitted the suspicious file to Dr.Web, but it appeared it was in the database already. I was able to find the virus and remove it from my computer. It was a nasty virus, because it disabled registry editing and didn't allow me to see hidden files and folders. But the major problem was that I wasn't able to delete the file from my HDD even with unlocker! Thank god Dr.Web was updated and it was able to detect the virus.

After scanning my computer with Dr.Web I decided to check again with Kaspersky Anti-Virus that protects my laptop. It found 8 more trojans and viruses on my computer.

I liked Dr.Web, NOD 32 and Symantec, but next time I will protect my computer only with Kaspersky (especially after the fact that the developer of AVZ works for Kaspersky now) or something else.